WEDNESDAY MAY 26, 2021
9:00 – 12:00 EARLY CAREER, YOUNG SCIENTISTS AND PhD SESSION13:30 Welcome words French and German societies
14:00 SESSION I: Dynamics of ECM in tissue repair and regeneration
discussion leaders: Sabine Eming (Germany) and Véronique Moulin (Quebec)
14:00 Sabine Werner, ETH, Zurich, Switzerland
Parallels between tissue repair and cancer: The fibroblast-matrix perspective (25 min + 5 min questions)
14:30 Bénédicte Chazaud, NeuroMyoGène Institute, University of Lyon, France
Different macrophage subsets control matrix remodeling during tissue repair and fibrosis during chronic diseases - highlights from the skeletal muscle
(25 min + 5 min questions)
15:00 3 or 4 presentations selected from abstracts (10 min each + 5 min questions each)
16h00 – 16h10 Break
16:10 - 16:40 Meet the speaker session
16:40– 17:20 Poster session(s)
17:20 KEYNOTE LECTURE: Suneel S. Apte, Lerner Research Institute, Cleveland, Ohio
Coupled genetics-degradomics for insights on cellular regulation by the matrix.
THURSDAY MAY 27, 2021
9:00 SESSION II: Cancer ECM and tumor immunitydiscussion leaders: Liliana Schaefer (Germany) and Ellen Van Obberghen-Schilling (France)
9:00 Emmanuel Donnadieu, Cochin Institute, University of Paris, France
Live imaging of T cells and the extracellular matrix in tumors
(25 min + 5 min questions)
9:30 Cathrin Brisken, EPFL, Lausanne, Switzerland
A special relationship with the matrix determines lobular breast cancer
(25 min + 5 min questions)
10:00 3 or 4 presentations selected from abstracts (10 min each + 5 min questions each)
11:00 – 11:10 Break
11:10 - 11:40 Meet the speaker session
11:40 – 12:20 Poster session(s)
LUNCH BREAK
13:30 SESSION III: Mechanobiology, remodeling and ECM stiffness
discussion leaders: Dieter Rheinhardt (Canada) and Laurent Duca (France)
13:30 Johanna Ivaska, University of Turku, Turku, Finland
Unexpected paradigms in cancer mechanobiology
(25 min + 5 min questions)
14:00 Benoit Ladoux, Institut Jacques Monod, University Paris Diderot, France
The impact of long-lived physicochemical footprints on cell migration paths
(25 min + 5 min questions)
14:30 - 15:00 Break
15:00 Farshid Guilak, Washington University, St. Louis, US
(25 min + 5 min questions)
15:30 3-4 presentations selected from abstracts (10 min each + 5 min questions each)
16:30 - 17:00 Meet the speaker session
17:00 - 17:10 Break
17:10 - 19:10 YOUNG INVESTIGATOR AWARD SESSION
(6 candidates : 3 german, 3 french) 10 min + 5-10 min questions
Lindsay B Alcaraz, Inserm U1194, University Montpellier, France
A 9-kDa SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment
Nicole Hecht, Research Centre for Experimental Orthopaedics, Heidelberg University Hospital
Mechanosensitive miRs regulated by anabolic and catabolic loading of human cartilage
Margaux Lecacheur, Inserm U1065, University Cote d’Azur, Nice, France
Mechanical activation of the collagen receptors DDR1 and DDR2 promotes melanoma aggressiveness through YAP pathway
Katrin Schönborn, Translational Matrix Biology, University of Cologne Collagen XII is a dose-dependent regulator of skin homeostasis and regeneration
Thomas Loustau, Karlsruhe Institute of Technology, Karlsruhe, Germany
Tenascin-C orchestrates an immuno-suppressive tumor microenvironment through CCL21/CCR7
Aline Zbinden, Department of Women's Health, University of Tübingen Impact of Extracellular Matrix Proteins on Pancreatic β-cell Function
19:15 - 20:15 GENERAL ASSEMBLY OF EACH SOCIETY
FRIDAY MAY 28, 2021
9:00 SESSION IV: Role of ECM in cell stemness and cell fate plasticitydiscussion leaders: Chloé Féral (France) and Kay Grobe (Germany)
9:00 Yekaterina A. Miroshnikova, Helsinki Institute of Life Science, University of Helsinki, Finland and Laboratory of Molecular Biology NIDDK, NIH, USA
Mechanical forces and the nucleus: regulation of cell fate and integrity
(25 min + 5 min questions)
9:30 Marisa Faraldo, Curie Institute, Paris, France
The role of laminin-binding integrins in mammary gland development and in the control of mammary stem/progenitor cells
25 min + 5 min questions)
10:00 3 or 4 presentations selected from abstracts (10 min each + 5 min questions each)
11:00 – 11:10 Break
11:10 - 11:40 Meet the speaker session
11:40 – 12:20 Poster session(s)
LUNCH BREAK
14:00 SESSION V : Trafficking and secretion of ECM components
discussion leaders: Shireen Lamande (Australia) and Laurent Muller (France)
14:00 Philippe Chavrier, Curie Institute, Sorbonne University Campus Pierre et Marie Curie, Paris, France
The protease-dependent invasion program of breast cancer cells
(25 min + 5 min questions)
14:30 David Stephens, School of Biochemistry, University of Bristol, UK
Intracellular trafficking and processing of procollagen
(25 min + 5 min questions)
15:00 4 or 5 presentations selected from abstracts (10 min each + 5 min questions each)
16:15 - 16:45 Meet the speaker session
16:45 – 17:15 Awards and closing remarks
Young Investigator Award presentation
SFBMEc Awards Presentation
German Society Awards Presentation
Closing Remarks